Eleven important Cancer questions.

 1.   How and why do Cancer cells grow in the absence of grow signals?

2.    How do Cancer cells ignore the signal for apoptoses?

3.    How and why do Cancer cells invade other areas of the body?

4.    How do Cancer cells signal blood vessels to grow toward tumours?

5.   How do Cancer cells hide from the immune system?

6.  How do Cancer cells trick the immune system into protecting them?

7.  Why do Cancer cells accumulate multiple changes in their chromosomes?

8.  Is Arginine a nutrient Cancer needs for survival? 

9.  How do cancer cells make energy from nutrients?

10. Why do Cancer cells have double the number of Chromosomes?

11. Does a vaccine need the immune system to be effective?

104 millions gallons of water removed from public national forest.

Hi Nelson, In 2023 alone, Nestlé-successor BlueTriton removed an astounding 104 million gallons of water from our public lands in the San Bernardino National Forest – water that should have been nourishing the forest and providing drinking water to the low-income communities that live below the San Bernardino Mountains.  Join us in telling the corporations behind this water theft: it’s GAME OVER! Nearly a year ago, we shared news that California water regulators found BlueTriton had failed to prove that it had a legal right to the tens of millions of gallons of water it was removing annually from the San Bernardino National Forest for bottling.  But BlueTriton’s lawyers quickly tied the Water Board decision up in the courts, leaving the decision about the future of Arrowhead Springs in the hands of the US Forest Service. Over the past year our team has repeatedly reminded the Forest Service of its legal responsibilities, submitted enforcement petitions, met with federal and state officials, filed public records requests and more.  Then, in June, we provided funding to help a local partner, Save Our Forest Association, sue the Forest Service to ratchet up the pressure even more.  That lawsuit has prompted a BIG decision – the Forest Service has ordered BlueTriton to turn off the tap once and for all, ending a decades-long theft of public water to which it had no right! Help us raise $10,000 for Save Our Forest Association and other local partners on the ground.   In a July letter denying BlueTriton’s request for a new permit, the Forest Service ordered the bottling giant to plug its boreholes, turn over the keys to its infrastructure and submit a plan for decommissioning its pipeline! And just last week, the Forest Service invited local advocates to meet to develop a plan for the restoration of Strawberry Creek, which has been dewatered by BlueTriton and its predecessors for decades. This is a huge win! But BlueTriton isn’t going down without a fight, so we’ve got to keep the pressure on.  And at the center of that fight is the local community, including grassroots groups and our longtime partner, Save Our Forest Association. We’ve got their back all the way, and we know you’ll help us get them all the resources they need!  Together, we’ve come a long way. Every member of the Story of Stuff Community should feel enormous pride in this accomplishment – you powered this campaign for nearly a decade! I also want to congratulate the local citizens – including longtime activists Steve Loe, Amanda Frye and Hugh Bialecki and others – who made countless personal sacrifices to keep the pressure on. As I wrote to you a year ago, water is life – and you and others have proved to the world through this campaign that it's well worth fighting f

ARGININE, A NUTRIENT CANCER UTILIZES.

https://www.science.org/doi/10.1126/sciadv.ade9120

A CANCER FIGHTING PAGE.

RESA ResEARCH ARTICLE 

on CANCER

Share on

Arginine limitation drives a directed 

codon-dependent DNA sequence evolution

 response in colorectal cancer cells.

DENNIS J. HSU HTTPS://ORCID.ORG/0000-0003-4200-1098, JENNY GAO HTTPS://ORCID.ORG/0000-0003-4682-7428, NORIHIRO YAMAGUCHI HTTPS://ORCID.ORG/0000-0001-8023-9748, ALEXANDRA PINZARU, QIUSHUANG WU HTTPS://ORCID.ORG/0000-0002-9301-3630, NANDAN MANDAYAM HTTPS://ORCID.ORG/0000-0002-4061-9348,

 MARIA LIBERTI, SØREN HEISSEL, HANAN ALWASEEM HTTPS://ORCID.ORG/0000-0002-4946-1436, [...], AND SOHAIL F. TAVAZOIE +1 authorsAuthors Info & Affiliations

SCIENCE ADVANCES

6 Jan 2023

Vol 9, Issue 1

DOI: 10.1126/sciadv.ade9120

12,6498

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Abstract

Utilization of specific codons varies between organisms. Cancer represents a       model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons are frequently mutated to other codons. Moreover, arginine limitation—a feature of tumor microenvironments—is sufficient to induce arginine codon–switching mutations in human colon cancer cells. Such DNA codon switching events encode mutant proteins with arginine residue substitutions. Mechanistically, arginine  limitation caused rapid reduction of arginine transfer RNAs and the stalling of   ribosomes over arginine codons. Such selective pressure against arginine codon translation induced an adaptive proteomic shift toward low-arginine codon–    containing genes, including specific amino acid transporters, and caused             mutational evolution away from arginine codons—reducing translational              bottlenecks that occurred during arginine starvation.                                                  Thus, environmental availability of a specific amino acid can influence DNA          sequence evolution away from its cognate codons and generate altered proteins.

What are Codons? https://en.wikipedia.org/wiki/DNA_and_RNA_codon_tables

THERE IS HOPE FOR THE FUTURE OF THE HIGH SEAS!

Nelson,   I’ve campaigned against deep sea mining for years, but I’ve never felt hope like this before.   I’m surrounded by an excited and determined Greenpeace delegation in Kingston, Jamaica, where government officials from around the world are about to discuss the future of the high seas. A debate over a moratorium on deep sea mining is finally on the agendaafter years of campaigning. This is our best chance yet to stop destructive mining before it begins. Now that the concrete protection of the international seabed is on the table, we need you to help sustain the months of relentless campaigning that lie ahead. Greenpeace Canada needs 169 more donations before midnight tomorrow to reach its $31,816 goal.   Please give $25 today to help us push world governments – including Canada’s – to support a moratorium on deep sea mining with bold action. Let’s stop this industry before it starts!   We’re closer than ever to stopping an industry that threatens to destroy some of the earth’s last untouched places. We must take every chance to show up in full force when key decisions are being made.   The movement we’ve built together, alongside Indigenous-led movements in regions that will be impacted the most, is strong and growing.    We’ve mobilized in deep sea mining hotspots, exposed industry lies about the safety of tearing up the seafloor, and made governments and the media pay attention to this new and extreme threat to the oceans.   A staggering number of people – over 2.8 million – have already signed Greenpeace’s petition to stop deep sea mining!   We’ve gained such momentum that 27 countries, including Canada, now support a moratorium, ban, or precautionary pause on deep sea mining, with the European Union and the United Nations sounding the alarm as well. This could be the turning point, but only if supporters like you keep boosting our action.   Please help us stop deep sea mining before it starts with a $25 donation before midnight tomorrow.   We must keep pushing governments to commit to a moratorium and show leadership and action on the world stage.   I know we can win this struggle against the mining of precious, untouched ecosystems. We’ve done it before. In the 1980s, Greenpeace campaigned with our supporters and allies to protect Antarctica and, in 1991, won a ban on commercial mining there. It’s time to do something similar for the deep seas!   Deep sea mining will pollute the water with its waste. It will disturb and destroy the habitats of a multitude of species, with scientists warning the damage could be irreversible. [1] Why risk all that when the oceans are already under threat from plastic pollution, overfishing, and overheating?   With your support, Greenpeace can speak out independently and continue to thwart the deep sea mining industry’s plan until a moratorium is agreed upon. Your gift before midnight tomorrow will help us stop a greedy industry from carving up the ocean floor.   Louisa Global campaign lead on deep sea mining, Greenpeace International SOURCES [1] Predicting the impacts of mining deep sea polymetallic nodules in the Pacific Ocean, May 2020, Mining Watch

This email was sent to: human4usbillions@gmail.com. You are receiving this email because you have signed up for the Greenpeace Canada mailing list.

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57 COMPANIES ARE RESPONSIBLE FOR 80% OF CARBON EMISSIONS.

57 Companies Are Responsible for 80% of polluting Carbon Emissions That Cause Both Climate Change and Cancer!

Sign Now

Joseph,   A new study just revealed that 80% of climate change-causing emissions come from just 57 companies around the world. Chevron, ExxonMobile, BP, Aramco, Gazprom, and the National Iranian Oil Company are several of the largest contributors to continually skyrocketing greenhouse gasses.   Consumers around the world are made to feel guilty and responsible for climate change, when in reality, a few powerful companies are primarily to blame. In fact, not only have these corporations been poisoning our world with their horrid carbon footprints, but they've also been doing so at a faster and faster rate.  In 2016, world leaders came together to craft the Paris Accord. Signatories were supposed to promise to reduce their countries' carbon emissions. But since that time, countries have let these corporations increase their carbon footprints. Most of these 57 companies surged their production and output of emissions, primarily related to fossil fuels, after the Paris Accord. That's why it's important for us to put public pressure on these corporations and on world governments to shift away from fossil fuels. Public pressure is an astoundingly powerful tool, and often very effective. We need to tell these corporations that we are watching, and that we won't let the status quo continue! Sign the petition to demand that Chevron, ExxonMobile, BP, Aramco, Gazprom, and the National Iranian Oil Company take responsibility for their carbon emissions. Their will not be a profit for any of them in the near future if they do not change now!  They can invest their money and power to plant trees and gardens: to create new Green Cities and alternative energy sources that do not pollute, to create water filtration plants that remove salt from the Ocean and pumps the water to arid regions of the planet, creating Green Oasis. They can join the Green Revolution instead of fighting it!  We must speak out today while we still have a planet to save!

Thank you, Miranda Care2 Petitions Team

P.S. These same 57 companies can help us fight climate change — and fast. Sign the petition.      Sign Now

A LETTER FOR THE CANADA REVENUE AGENCY and associates in Winnipeg.

TO: CANADA.CA/ARC-INFO-SOURCE

 CANADA REVENUE AGENCY.

Your impersonal department just taxed me a total of $8000 Dollars this month of July, 2024. Please allow me to make it personal for you and your entourage. I am a Seventy Six years old Colorectal stage 4 Cancer patient. The money you believe is my revenue derives from Fifty years of hard labor repairing and renting my old house to low income families with children and their pets. I finally had to sell the family property because the burden of municipal, Federal and Provincial taxes, plus the cost of repairs, finally broke me! I placed half  the money from the house sale into government bonds and the other half into your TFSA; and then I waited a year for the bonds to mature.  A year later, after living cash free, I made the naive mistake of placing the money from the bonds into the TFSA. I am positive you understand that people who live in poverty for many years, and are suddenly provided with money, often make economic mistakes costing them dearly. $8000.Dollars, for example. You penalized me $8000. for putting too much of my own money into your so called "Tax Free savings Account"! 

Conclusion. TFSA's are a trap for suckers! Nobody should use them! Now that we’ve become personal, I am sure you won’t mind if I publish this letter on my world wide blog. Thanks for reading

Signed: Joseph N. Raglione

Executive director, The World Friendly Humanitarian Peace and Ecology Movement.

human4us2.blogspot.com

human4usbillions@gmail.com

==================================================

Summary of service feedback

Compliment details

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I COMPLIMENT YOU FOR DOING A GOOD JOB TAXING ELDERLY CANCER PATIENTS. I AM ONE OF THOSE PATIENTS. I AM SEVENTY-SIX YEARS OLD WITH COLORECTAL STAGE FOUR CANCER AND THIS MONTH YOU TAXED ME $8000.DOLLARS, ACCORDING TO YOU, MY CLASS A ACCOUNTANT IN QUEBEC, MADE MISTAKES ON MY TAX PAPERS. ANY MONEY I AM FORCED TO SEND YOU IS DERIVED FROM THE SALE OF MY OLD HERITAGE HOUSE AND PROPERTY. I HAVE BEEN SURVIVING ON THE PROCEEDS OF THAT SALE FOR THE LAST FEW YEARS BUT THE CASH IS DWINDLING AND IF I SURVIVE, I WILL BE BACK ON THE STREET AND YOU WILL HAVE ONE LESS HUMAN-BEING TO TAX.

 AGAIN, CONGRATULATIONS! HUMAN4US2.BLOGSPOT.COM HUMAN4USBILLIONS@GMAIL.COM