HUMAN GENES THAT HIDE CANCER CELLS FROM THE IMMUNE SYSTEM...

1.    CD47... (THE "DON't EAT ME" SIGNAL.

2.    CD274 / PD-L1 (THE T-CELL "BRAKE")

3.    SOX17 (EARLY-STAGE "INVISIBILITY")

4.    B2M (DEFECTIVE "TARGETING")

5.    SETDB1 ("A GENETIC OFF-SWITCH.

6.    DUX4  (PREVENTS IDENTIFYING VARIOUS CANCERS.

7.    APMAP  (ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN...A PROTEIN CODING GENE UNDER STUDY IN HUMANS, IT IS INVOLVED IN ("FAT CELL BIOLOGY") 

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 AN IMPORTANT QUESTION.

WHY DO T CELLS NOT RECOGNIZE AND KILL MC38-K CELLS?

ANSWER...OUR IMUNE SYSTEM 'T' CELLS FAIL TO RECOGNIZE AND KILL CANCEROUS MC38-K CELLS PRIMARILY BECAUSE "KEY ANTIGEN-PRESENTATION MACHINERY" HAS BEEN DISABLED, MAKING THE TUMOR EFFECTIVELY "INVISIBLE" TO T CELLS.