The following Two year old article explains the facts about Vladimir Vladimirovich Putin who is the current dictator of Russia. Putin is not a President as he claims but he is an active and dangerous dictator along the lines of Stalin and Hitler. He is currently attacking the Ukrain with the full intent of annexing it back to Russia. He scorns the United Nations International treaty forbidding one country from attacking another. He is intent on rebuilding the old Soviet Empire which lasted until 1991 when, on that date, the people of the Ukrainian voted to regain their independence and leave the suffocating influence of the old Soviet Union.      N,J.R .

By Hanna Kozlowska

Investigative reporter

Published December 16, 2016This article is more than 2 years old.

Many key figures—including president Barack Obama, members of the Electoral College, and senate majority leader Mitch McConnell—have voiced concerns about Russia’s hacking campaign during the US election and its ties to the incoming administration. But leave it to Arizona senator and longtime Kremlin critic John McCain to bluntly explain why the United States should be worried.

“Vladimir Putin is a thug and a murderer and a killer and a KGB agent,” McCain said on CBS’s “Face of the Nation” on Dec. 11. Speaking two days later about Rex Tillerson, Trump’s pick for secretary of state, who received the Russian “Order of Friendship” in 2013, McCain said in a radio interview: ”Frankly, I would never accept an award from Vladimir Putin because then you kind of give some credence and credibility to this butcher, this KGB agent, which is what he is.”

Putin, who has ruled Russia since 2000, has created a regime under which his opponents are murdered; political prisoners are sent to Siberia for decades behind bars; minority rights are suppressed; opposition is quashed; foreign territory is forcefully annexed; and Syria’s bloodthirsty president, Bashar Assad, enjoys direct military support for his massacres.

Here’s a non-exhaustive list of examples of Putin’s abusive rule in Russia.

Murdering enemies.  

Putin, who has ruled Russia since 2000, has created a regime under which his opponents are murdered; political prisoners are sent to Siberia for decades behind bars; minority rights are suppressed; opposition is quashed; foreign territory is forcefully annexed; and Syria’s bloodthirsty president, Bashar Assad, enjoys direct military support for his massacres.

Murdering enemies

The list of people suspected murdered on orders from the Russian leader or people close to him is long. It includes several of Putin’s early critics among them liberal politician Boris Nemtsov, investigative journalist Anna Politkovskaya, and exiled former Russian spy Alexander Litvinenko. A UK government report showed that Litvinenko’s death—he was poisoned using polonium in London—which was “probably” approved by Putin. 

Click on the names to find the articles pertaining to these victims.

The list of people suspected murdered on orders from the Russian leader or people close to 

HOME BIOLOGY NEWS

Complex Three-Dimensional Kidney Tissue Created in the Lab From Scratch 

TOPICS:BiotechnologyKidneyOrgan TransplantStem CellsTissue

By KUMAMOTO UNIVERSITY FEBRUARY 1, 2022

Researchers in Japan have generated a kidney-like 3D tissue, consisting of extensively branched tubules, from cultured mouse embryonic stem cells. Credit: Dr. Shunsuke Tanigawa

A research team based in Kumamoto University (Japan) has created complex 3D kidney tissue in the lab solely from cultured mouse embryonic stem (ES) cells. These organoids could lead the way to better kidney research and, eventually, artificial kidneys for human transplant.

By focusing on an often-overlooked tissue type of organoid generation research, a type of organ tissue made up of various support and connective tissues called the stroma, Dr. Ryuichi Nishinakamura and his team were able to generate the last of a three-part puzzle that they had been working on for several years. Once the three pieces were combined, the resulting structure was found to be kidney-like in its architecture. The researchers believe that their work will be used to advance kidney research and even lead to a transplantable organ in the future.

Researchers in Japan have generated a kidney-like 3D tissue, consisting of many types of kidney-specific structures, from cultured mouse embryonic stem cells. Credit: Dr. Shunsuke Tanigawa

The kidney is a very important organ for continued good health because it acts as a filter to extract waste and excess water from blood. It is a complex organ that develops from the combination of three components. Protocols have already been established by various research teams, including Dr. Nishinakamura’s team at the Institute of Molecular Embryology and Genetics (IMEG) at Kumamoto University, to induce two of the components (the nephron progenitor and the ureteric bud) from mouse ES cells.

In this, their most recent work, the IMEG team has developed a method to induce the third and final component, kidney-specific stromal progenitor, in mice. Furthermore, by combining these three components in vitro, the researchers were able to generate a kidney-like 3D tissue, consisting of extensively branched tubules and several other kidney-specific structures.

The researchers believe that this is the first ever report on the in-lab generation of such a complex kidney structure from scratch. The IMEG team has already succeeded in inducing the first two components from human iPS cells. If this last component can also be generated from human cells, a similarly complex human kidney should be achievable.

“We are now working very hard to generate a fully functional human kidney,” said Dr. Nishinakamura. “We hope to use our developments to screen drugs for various diseases, and for transplantation in the long run.”

Reference: “Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma” by Shunsuke Tanigawa, Etsuko Tanaka, Koichiro Miike, Tomoko Ohmori, Daisuke Inoue, Chen-Leng Cai, Atsuhiro Taguchi, Akio Kobayashi and Ryuichi Nishinakamura, 1 February 2022, Nature Communications.
DOI: 10.1038/s41467-022-28226-7

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PIG HEART KEEPS MAN ALIVE! FANTASTIC BREAKTHROUGH!

'NEW HEART STILL A ROCK STAR': Man doing well after receiving first heart from gene-edited pig

PIG KIDNEYS PLAY A ROLE: Alabama doctors advance organ transplantation with gene-edited pig kidneys

The team said their research with the silicone cap and the drug cocktail is far from done. They add that it may be possible to strengthen or add to the drug cocktail to help regenerate fully complete limbs with actual toes and bones. Michael Levin, director of the Allen Discovery Center at Tufts and a study co-author, said the next step is to test the procedure out on mammals, which eventually could lead to human regeneration.

A team at Tufts University and Harvard University has brought scientists a step closer to the goal of regenerative medicine by using a drug cocktail to regrow a frog's amputated legs. 

Only a few animals in the world are able to regrow some limbs: salamanders, lizards and crabs. They do it through blastema cells, when a mass formation of stem cells occurs at the end of a stump almost immediately after the limb is lost, so the regrowth process can begin.

Frogs are like humans and mammals, however, in that they cannot regenerate complex limbs like arms or legs. Instead, our bodies, along with those of frogs, use scar tissue to protect wounds from blood loss and infection.

In a peer-reviewed study published in the journal Science Advances on Wednesday, scientists from the two universities wanted to see whether limbs could be regenerated on African clawed frogs with amputated legs. 

Tufts scientists created a five-drug-cocktail silicone cap. In the cap were drugs meant to reduce inflammation, a protein substance to help with scarring, and drugs meant to help the growth of blood vessels, muscles and nerve fibers. The team put the cap on the frogs for 24 hours. 

"Using the BioDome cap in the first 24 hours helps mimic an amniotic-like environment which, along with the right drugs, allows the rebuilding process to proceed without the interference of scar tissue," David Kaplan, professor engineering at Tufts and co-author of the study, said in a news release. 

The cap was taken off after the 24 hours, and the team spent the next 18 months observing any changes. At the end of the period, many of the tested frogs had not only regrown the legs, but the limbs also had become nearly fully functional.

The legs had a new bonelike structure, internal tissues and new "toes" without bones. They responded to touch, and the frogs were able to use them to swim and go back to a normal way of life. Nirosha Murugan, researcher at the Allen Discovery Center at Tufts and lead author of the study, said it was "exciting" to see the drugs helped create "an almost complete limb."

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"The fact that it required only a brief exposure to the drugs to set in motion a monthslong regeneration process suggests that frogs and perhaps other animals may have dormant regenerative capabilities that can be triggered into action," Murugan said.

Follow Jordan Mendoza on Twitter: @jordan_mendoza5.

Fossil fuel pollution = global warming = pandemics = death!

Nelson,   Two weeks ago, on an extraordinarily cold winter day, a group of Greenpeace volunteers and I visited 12 bank branches of the Big Five in Toronto – precisely, RBC, TD, Scotiabank, BMO and CIBC.We postered, went live on Instagram, and reminded everyone of the Big Five’s ongoing role in funding fossil fuel projects that violate Indigenous rights and accelerate climate chaos even as they continue to try to greenwash themselves. [1]   Together, we need to demand that Canada’s Big 5 banks stop funding destructive fossil fuel projects. Will you join me in doing so?

Yes, I will!

The CGL pipeline severely violates Indigenous rights and increases fossil fuel production. While Canada’s big 5 banks have made public commitments to achieve net zero emissions by 2050 [2] and to respect Indigenous land rights, their actions speak louder. And they are funding CGL, even as the Royal Canadian Mounted Police repeatedly raided unceded Wet’suwet’en territory in acts of colonial violence. [3] [4] [5] [6]   If you’re a customer of Canada’s Big 5 banks, remember that these banks are using YOUR money, YOUR savings to fund such projects. Tell them you don’t approve.

Send a message to the banks

It’s not at all impossible to stop investing in destructive pipelines or fossil fuel projects. A recent Greenpeace report shows that although the big 5 banks are more exposed to climate risk than they admit, they could phase out their support for fossil fuels. [7] I hope you can join me in telling them to do so.   Thank you for your support!   Tara, Mobilizations Campaigner, Greenpeace Canada

Sources   [1] https://www.greenpeace.org/canada/en/act/fossil-banks/  [2] https://cba.ca/banks-in-canada-committed-to-a-net-zero-economy-by-2050   [3] https://twitter.com/Gidimten/status/1478603962773245953 [4] https://www.theenergymix.com/2021/10/19/gidimten-checkpoint-urges-investors-to-dump-coastal-gaslink-pipeline/  [5] https://thetyee.ca/News/2022/01/10/BC-NDP-Faces-Internal-Pressure-Change-Course-Wetsuweten-Crisis/  [6] https://www.cbc.ca/news/canada/british-columbia/15-arrests-journalists-wetsuweten-cgl-1.6256696  [7] https://www.greenpeace.org/canada/en/press-release/49591/canadian-banks-defying-climate-science-by-increasing-fossil-fuel-finance/

Greenpeace doesn't accept any money from companies or governments so we can be independent and challenge anyone who threatens the planet or peace. To help us keep fighting climate change, defending our oceans and protecting ancient forests, please make a regular donation or start a fundraiser. Thank you!   You can grow the movement for a green and peaceful future. Forward this email and share the signup link for our regular email updates and ways to take action.   This email was sent to:human4usbillions@gmail.com Are we sending too many emails? Click here to receive fewer emails.

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900,000 DEATHS REPORTED IN THE U.S.

Sign up for this newsletter Read online Important developments in the pandemic.       By Derek Hawkins  Email  The Post's coronavirus coverage linked in this newsletter is free to access from this email.   The latest With omicron variant cases trending downward, a growing number of Americans say they're ready to live with the coronavirus and move on. Polls indicate Americans are comfortable taking more risks as the virus continues to circulate, accepting the possibility that they may eventually get covid-19 and that, if they're vaccinated and boosted, it probably won't be too bad. They are reviving plans they canceled earlier in the pandemic, resuming the activities they put on hold.  We’ve been here before, of course. And we know that we're one variant away from going through the same cycle again. But prior experience tells us that the more people move on, the harder it will be to reverse course if cases resurge. As more Americans adapt to a new normal, some states are moving to lift their school mask mandates. The Democratic governors of New Jersey and Delaware say they intend to phase out school masking requirements next month. Others may follow, with the governors of New York and Connecticut saying they would address the issue soon. But infections are still running extremely high relative to previous waves, andnot everyone is on board. In Virginia, some students aren’t ready for such a change, worrying that a future without vaccine or mask requirements could upend hard-won pandemic protections.  The Centers for Disease Control and Prevention is updating its booster guidance for people with weakened immune systems. The change would shorten the period between the initial vaccine series and the booster dose from five to three months for organ transplant patients and others whose medical conditions blunt their immune response. The move came as the United States marked 900,000 coronavirus deaths. “They were beloved mothers and fathers, grandparents, children, brothers and sisters, neighbors, and friends," President Biden said in a statement. He called on all Americans to get the vaccines and boosters.  Businesses laid off employees in droves in the pandemic’s early waves. This time, companies are struggling to hire and retain workers. Analysts predicted omicron would wreak havoc on the labor market, but January's strong job numbers showed how this part of the economy has become surprisingly variant-proof. “Employers did not yank job postings and run for the hills," one economist told The Washington Post. "Hiring remained robust and in the end, the economy barely sneezed.”    Other important news Do coronavirus tests work if shipped in freezing weather? Probably. Protests against public health mandates in Canada have intensified. Canadian police have made arrests, issued tickets, and seized fuel and vehicles. Australia plans to reopen to vaccinated tourists next month. The country had one of the world's strictest and longest-lasting border closures.  “Air rage” incidents surged on flights during the pandemic. Delta Air Lines has asked the Justice Department to help set up a “no-fly” list of unruly passengers.  Get breaking news alerts, offline reading lists and more. Download the app     Guide to the pandemic Track confirmed cases, hospitalizations and deaths in the U.S.and the spread around the world. U.S. vaccine distribution and delivery, tracked by state. Guides: Booster shots | Finding vaccine appointments | Vaccines | Variants | Masks Follow live updates about the pandemic from Post reporters across the globe. Submit a question and we may answer it in a future story or newsletter.    Your questions, answered "Can vaccines and boosters protect someone from developing long covid if they end up getting infected?" — Kim in Virginia Research suggests that vaccines and boosters do protect you from long covid in two important ways: first, by preventing you from getting sick in the first place; and second, by reducing the incidence in those who get breakthrough infections.  Long covid has flummoxed researchers and doctors since the early days of the pandemic. Millions of people around the world have reported fatigue, shortness of breath, difficulty concentrating, and other problems that last long after infection. There's no firm definition for this condition, and no definitive diagnosis, but it's generally described as symptoms persisting for several weeks or more. A recent non-peer-reviewed study out of Israel found that people who'd gotten two doses of the Pfizer-BioNTech vaccine were far less likely to report common long covid symptoms than unvaccinated people. Researchers spoke with more than 3,000 people who had tested positive. According to the results, vaccinated patients were 54 percent less likely to report headaches, 64 less likely to report fatigue, and 68 less likely to report muscle pain than those who weren't vaccinated. Another study released in September produced similar findings. Researchers looked at data from more than 1 million users of a covid-19 symptom tracker app in the United Kingdom and found the risk of long covid was slashed by half in those with two vaccine doses.  "The reasons for vaccination beyond the most pressing need to avert severe disease and deaths are manifold, but foremost it is to prevent long COVID,” Anthony De Soyza, an expert in respiratory medicine at the British National Institute of Health Research, said of the study in the Lancet medical journal. It's not clear why vaccines may ward off long covid in infected people — in large part because scientists don't know what causes this condition to begin with. One possibility, as described by the journal Nature in November, is that the immune protection generated by vaccines stops the virus before it can establish viral “reservoirs” in the body that may be linked to long covid. Whatever the case, the research isn't conclusive, and the data was collected before omicron peaked. Like so much related to long covid, vaccines and boosters, scientists need more time to observe the real-world effects of the disease and prevention efforts before we get a firmer answer. The unfortunate reality about long covid is that anyone can get it, regardless of their vaccination status or even the severity of their illness. Many cases resolve on their own after a few weeks or months, while some people experience debilitating symptoms that last much longer.  But the latest data is encouraging — as is the fact that two separate studies independently reached similar results.    Today’s top reads Find more stories, analysis and op-eds about the pandemic on our coronavirus page. I’m disgusted by Joe Rogan’s weak apology. My former colleague’s death at 47 makes it worse.  Perspective ●  By Margaret Sullivan ●  Read more »   Vincent Zhou out of men’s figure skating event after positive test clouds U.S. team’s silver By Les Carpenter ●  Read more »   England’s oldest pub, possibly 1,229 years old, shuts doors due to coronavirus hardships By Annabelle Timsit ●  Read more »   GOP rivals seize on Stacey Abrams’s maskless classroom photo as her campaign calls criticism ‘silly’ By Reis Thebault ●  Read more »        We think you’ll like this newsletter Check out A Better Week for a 7-day email course that will help you conquer your calendar, get more done and find time for the things you care about. Sign up »

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