Thursday, March 7, 2019

Doctors are scientists.


Why Should We Listen to Scientists?


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Gentle People:
 If by accident you cut off your finger, will you take your finger to a Doctor or a Priest? Which one learned enough science to put your finger back on? A good question for people who do not trust science and place their faith in a comforting religion...    N.J.
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There’s a game young children like to play when they’re just beginning to learn how to interact with the world, talk to others, and indulge their natural curiosity: it’s called the “Why?” game. Take some natural phenomenon: Why is it raining? Why do people die? Why is the sky blue? If you furnish the child with an answer, they’ll inevitably ask “Why?” again, until you reach the limits of your knowledge (or your patience), and snap back with an unsatisfying: “Because that’s just how it is.”
Most people eventually grow out of the “Why” game. This is partly because, as a conversational strategy, it’s irritating. But also, people come to terms with there being a set of fundamental “whys” where the answers won’t necessarily be clear. You can fill this gap with your religion, or with something like the multiverse theory combined with the weak anthropic principle, or any number of other philosophical explanations. You can use a nice healthy dose of pragmatism and choose to worry about more pressing matters before trying to solve the mysteries of the universe.
But the “Why” game is still a useful one to play as an adult, testing each link in the chain of your beliefs, exploring your own motivations, and examining the trends and forces behind changes in society. So, in this spirit, I’ll ask a question that’s been more and more popular lately: “Why should I listen to scientists?”
This question is leading politicians towards inaction on climate change, individuals towards not vaccinating their kids, and consumers to oppose genetic modification of foods, just as social media—where every opinion seems to have equal weight—leads thousands of people into bizarre conspiracy-theory wormholes.
As the world grows more complex and interconnected, with threats from emerging technologies, biodiversity collapse, and climate change, it’s more necessary than ever that we work together in a rational, constructive way. But when you start from irreconcilable standpoints about what is true, or even how to find truth, practical problem-solving becomes impossible. So how can we persuade people that expertise isn’t overrated?

That Which Can Be Proven

For many of the sciences, especially physics, the answer to this question was once obvious: the experts are right. Verifiably, nigh-on indisputably, their theories have the power to make accurate predictions that competing world views cannot make. Newtonian mechanics, when its laws were applied properly, could predict how the stars and planets would move. When Einstein’s theory of general relativity superseded Newton’s gravitational law, this was confirmed by a famous expedition to observe the deflection of light during an eclipse, a prediction that general relativity made which Newton’s gravity could not explain.
On the surface, this line of argument is persuasive—but it is also flawed, and far from universal. What if the theory is complicated enough that drawing that straight line—from theory to prediction to observation that confirms the theory—is far from obvious? Why should people believe it then?
The invention of writing has allowed scientific and technological knowledge to accumulate over thousands of years, and people have had to specialize to a greater and greater degree: the age of polymaths who knew everything is over, and, as the economists like to say, no individual person can make a pencil. Instead, more often than not, you have to study and hone your expertise for many years, in ever-narrower fields, to make a contribution to our understanding of the world. In physics, for example, Nobel Prizes are increasingly won not by individual geniuses, but by ever-larger collaborations of scientists, running experiments that cost billions upon billions of dollars.

That Which Cannot

This is before we consider newer sciences with larger uncertainties attached. Climate science is a prime example, where the complexity and inherent uncertainties associated with the system that’s being analyzed prevent us from making absolute statements about precisely how, for example, rainfall patterns will shift if we continue to emit carbon dioxide into the atmosphere for the rest of this century.
So scientists make predictions with uncertainties attached; when you read climate change reports like those from the IPCC, their claims are ranked according to confidence levels. Things like “more greenhouse gas emissions will increase temperature” are practically certain with the current state of scientific knowledge, but precisely how complex systems like the Antarctic ice sheets will respond is still a subject for scientific inquiry and debate.
Similarly, you’re probably familiar with an endless parade of headlines proclaiming that red wine, or chocolate, or caffeine, are “good for you” or “bad for you.” The human body is an extremely complex system, and a crisis of reproducibility means plenty of studies can be reattempted with contradictory results.
In light of all of this, we must still persuade people of the truth: that science remains humanity’s best tool to understand the universe, to survive, and to flourish. That far from ignoring scientists and experts, we need them to take on a greater role.
We need a different kind of faith: trust that the institutions of science are behaving in an honest and rigorous way. We cannot simply answer the “Why” question with “Because science says so” and pretend that scientific knowledge is indisputable in all cases—even in areas where there is active debate. In the age of social media, where experts who’ve spent decades studying an issue have equal platforms with the gut instincts of strangers, people feel freer to believe whatever they prefer to be true.

The Values Behind It All

Professor Harry Collins, a sociologist of science, suggests that rather than portraying science as a fount of utter certainty, we should focus instead on its values. If you present uncomfortable knowledge as reams of technical jargon, or handed down from on high by geniuses who you couldn’t possibly understand, people will feel attacked. Present the working method of the scientific community, and people will recognize values that they treasure. Science relies on observations and logical deductions. It is open to criticism—and scientific research is usually picked apart by fellow scientists before it can be published.
The greatest rewards aren’t for reinforcing existing paradigms, but coming up with totally new discoveries or theories that can persuade people to abandon the old paradigms. Scientific knowledge should be corroborated, and the mechanisms for finding it should be reproducible.
Scientists can disagree with each other, and they can be wrong, but they show their working and the evidence that they rely on. So, Collins argues, your trust in scientific conclusions should rest on the openness, collaboration, and expertise of those making the claims. Scientists can point to a track record of successful predictions, or to the mountains of evidence, thought, and theory behind what they say; but they can also point to the set of values that means you should trust their conclusions.
But this requires a change in perspective from the sciences and those that promote them. Most of all, we must stay true to the mission of the sciences: not as servants of profit or privilege, but of seeking truth so that we all might live better lives.

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Thomas Hornigold is a physics student at the University of Oxford. When he's not geeking out about the Universe, he hosts a podcast, Physical Attraction, which explains physics - one chat-up line at a time.

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Sunday, February 24, 2019

Will young P.M Trudeau lose the next election? Yes? No?



         THE WORLD FRIENDLY PEACE AND ECOLOGY MOVEMENT DOES NOT AGREE WITH CANADIAN PRIME MINISTER JUSTIN TRUDEAU AND HIS ENVIRONMENT MINISTER THAT A TRANS MOUNTAIN PIPE LINE IS JUSTIFIED AND NECESSARY FOR THE ECONOMY OF CANADA. WE SUPPORT THE NEW DEMOCRATIC PARTY AND ALSO GREENPEACE CANADA IN THEIR EFFORTS TO STOP THE DANGEROUS PIPELINE.
WE BELIEVE A FUTURE WITH CLEAN AIR AND WATER IS NECESSARY FOR THE WELL BEING OF BOTH ORCA WHALES AND CANADIAN CHILDREN.
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Orcas Vs. Trans Mountain

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Christy Ferguson, Greenpeace Canada/

Feb 22, 2019, 4:11 PM (2 days ago)

Images are not displayed. Display images below - Always display images from greenpeace.canada@act.greenpeace.org
Gentle People:
You might have seen the news today… 
The National Energy Board has recommended approving the Trans Mountain pipeline — in spite of the catastrophic risks it poses to the last remaining southern resident orcas.
More than ever, it’s clear just how much the federal government is willing to risk for this dangerous pipeline, from the loss of an iconic species to mounting costs for taxpayers and the climate.
You can be assured we won’t let this news stop our determination to stand up for the climate, endangered species and Indigenous rights in the battle to come. But we can’t keep up the momentum without your support.
If you’ve been on the fence till now, this is the time to join us. We’re closing in on our deadline to bring aboard 600 new monthly donors this month. With less than seven days to go, we need all the support we can gather now to power our vital campaigns — and stand up against tar sands pipelines — in 2019. Will you join us with a $15/month donation to protect the planet?  
You might be thinking, “If I don’t sign up now, someone else will.” But consider that just 0.2% of the people who have opened our emails have joined us as a monthly donor so far this month. We really are counting on you.
We face some huge challenges here in Canada as we work to protect the climate, endangered species, and uphold Indigenous rights in the face of rapid expansion of the tar sands. We work in two languages and have offices in Montreal, Toronto, Ottawa and Vancouver. We keep our overheads low and stretch your dollar as far as it can go — but with rising expenses year-on-year, we can only scale up our ambition with many more monthly donors joining us. 
We don’t accept a cent of funding from corporations and governments, because our independence makes us an effective voice for the planet. This means that everything we do is thanks to monthly donations from people like you. 
I would be so grateful if you’re one of the 88 supporters who joins us at this urgent moment to reach our goal. By joining today for $15 a month, you will become part of a global movement working to confront the biggest environmental threats of our time. 
It just takes a couple of clicks. And then you’ll be adding your power behind one of the strongest independent voices for the planet out there. 
Please join us now.
Thanks so much in advance. 
Christy
Executive Director (Interim), Greenpeace Canada

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A Genetic Code update.

Scientists Just Added Four New Letters to the Genetic Code

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A four-letter alphabet might seem limited, but it’s all nature needed to write the instructions for all life on the planet. News that researchers have added four letters to the genetic alphabet opens the door to new possibilities in synthetic biology, data storage, and even the search for life beyond our planet.
The genetic code at the heart of all living things is elegantly simple. Each half of the famous double helix structure is built from four small molecules called bases: adenine, thymine, cytosine and guanine (ATCG). The order in which they appear determines what the DNA codes for, just like series of zeros and ones at the hearts of computers do.
But now scientists at the Foundation for Applied Molecular Evolution in Florida have successfully added four new bases to create what they are calling “hachi-moji DNA” (eight-letter DNA in Japanese), doubling the potential information density of genetic code.
This isn’t the first attempt at expanding the genetic code. In 2014, scientists at the Scripps Research Institute in California unveiled DNA with two extra bases, and in 2017 they showed that they could get bacteria to use this code to build proteins that don’t exist in nature. But the new work not only adds an extra two bases, it also sticks more closely to the blueprint used by nature.
The double helix of DNA is held together by hydrogen bonds between complementary bases—A pairs with T and C pairs with G. The Scripps research used water-repelling molecules that stick together but repel the other bases. These bases need to be sandwiched between natural bases, so it’s not possible to have extended stretches of unnatural bases limiting what they can code for.
Hachi-moji DNA, however, uses hydrogen bonds just like natural DNA to link its two new pairs—S with B and P with Z—and the bases are also capable of appearing next to each other. Because DNA is read in triplets of bases called codons, each of which codes for a particular amino acid, this significantly increases the number of potential codons compared to the previous approach: 4,096 compared to conventional DNA’s 64.
The experiments also suggest hachi-moji DNA preserves all the key characteristics required to support Darwinian evolution, crucial for supporting life. The bases pair reliably, the structure remains stable regardless of the sequence of bases, and they’ve demonstrated that it can be copied into RNA.
That’s crucial, because while DNA holds the blueprints for an organism, in order for cells to do anything with that information it has to be converted into the mobile, single-stranded molecule RNA, which can act as instructions for protein factories called ribosomes or can help regulate genes.
In terms of potential uses for the new letters, the possibilities are broad. All of nature’s complexity has been created from the 20 amino acids conventional DNA can produce (multiple codons code for the same amino acid). New codons make it possible to code for new amino acids with novel properties, which could enable everything from more powerful medicines and industrial catalysts to more outlandish ideas, like electrically-conducting proteins.
That will require a huge amount of work on tools that can take advantage of the new code, though, the scientists behind the research admitted to Wired. A potentially nearer-term goal might be to take advantage of the extra information density to boost efforts to see DNA as a super-compact and stable form of long-term data storage.
Perhaps the biggest contribution of the research is the window it gives us into the potential forms life could take. The new code is a long way from supporting self-sustaining organisms—the researchers have yet to demonstrate that the code can be replicated by cells, and it is reliant on supplies of lab-created building blocks that aren’t available in nature.
But the fact that you can replicate the form and function of DNA with very different constituent parts suggests that life beyond Earthmay be unlike anything we have seen before. The research was funded by NASA, and representatives told CNN that they hope it will help them expand the scope of their search for extraterrestrial life.
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I am a freelance science and technology writer based in Bangalore, India. My main areas of interest are engineering, computing and biology, with a particular focus on the intersections between the three.

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Saturday, February 23, 2019

No Nuclear missiles in space, please!

Gentle People:

 I do not appreciate a potential for nuclear explosions in outer space polluting the atmosphere that protects life on Earth! Thanks to Donald Trump and his new space force, the possibility of nuclear explosions in space ripping away and polluting our thin layer of atmosphere now becomes a U.S. Republican political reality. I doubt if anybody else on Earth will take the U.S. president seriously because the consequences of a race to arm space with deadly Nukes or Lasers will be disasterous to the co-operation presently existing between technological nations. The International Space Station is a good example of the de-tente existing between countries interested in developing outer space for the benefit of humanity. It is basically a United Nations in space and its neutrality must be protected from political megalomaniacs and dictators back down on Earth.

 It is possible to ring the Earth with dangerous satelites capable of destroying each other and possibly harboring a Nuclear war head or Two and that possibility must be banned here and now! We must create another international Non-Proliferation Treaty with outer space included in the treaty.

 We only have approximately Three miles of atmosphere between us and the dark cold void of space and destroying that atmosphere won't take long if we allow it to happen! The good news is that World Scientists and every Astronaut connected with the International Space Program have bonded in friendship and believe that space is a good place for creating science experiments aimed at helping humanity. For decades the I.S.S. has housed Astronaut Scientists from around the world working together without fear of political interference from dominating governments. That will continue long after dictators have been removed from office.

The Nuclear Non-Proliferation Treaty (NPT), 1968

The Nuclear Non-Proliferation Treaty was an agreement signed in 1968 by several of the major nuclear and non-nuclear powers that pledged their cooperation in stemming the spread of nuclear technology. Although the NPT did not ultimately prevent nuclear proliferation, in the context of the Cold War arms race and mounting international concern about the consequences of nuclear war, the treaty was a major success for advocates of arms control because it set a precedent for international cooperation between nuclear and non-nuclear states to prevent proliferation.
After the United States and the Soviet Union signed the Limited Test Ban Treaty in 1963, leaders of both nations hoped that other, more comprehensive agreements on arms control would be forthcoming. Given the excessive costs involved in the development and deployment of new and more technologically advanced nuclear weapons, both powers had an interest in negotiating agreements that would help to slow the pace of the arms race and limit competition in strategic weapons development. Four years after the first treaty, the two sides agreed to an Outer Space Treaty that prevented the deployment of nuclear weapons systems as satellites in space. Of far greater import, Soviet and U.S. negotiators also reached a settlement on concluding an international non-proliferation treaty.
By the beginning of the 1960s, nuclear weapons technology had the potential to become widespread. The science of exploding and fusing atoms had entered into public literature via academic journals, and nuclear technology was no longer pursued only by governments, but by private companies as well. Plutonium, the core of nuclear weapons, was becoming easier to obtain and cheaper to process. As a result of these changes, by 1964 there were five nuclear powers in the world: in addition to the United States, the Soviet Union, and the United Kingdom, all of which obtained nuclear capability during or shortly after the Second World War, France exploded its first nuclear bomb in 1960, and the People's Republic of China was not far behind in 1964. There were many other countries that had not yet tested weapons, but which were technologically advanced enough that should they decide to build them, it was likely that they could do so before long.
The spread of nuclear weapons technology meant several things for international lawmakers. While the only countries that were capable of nuclear strike were the United States, its close ally Britain, and the Soviet Union, the doctrine of deterrence could be reasonably maintained. Because both sides of the Cold War had vast stocks of weapons and the capability of striking back after being attacked, any strike would likely have led to mutually assured destruction, and thus there remained a strong incentive for any power to avoid starting a nuclear war. However, if more nations, particularly developing nations that lay on the periphery of the balance of power between the two Cold War superpowers, achieved nuclear capability, this balance risked being disrupted and the system of deterrence would be threatened. Moreover, if countries with volatile border disputes became capable of attacking with nuclear weapons, then the odds of a nuclear war with truly global repercussions increased. This also caused the nuclear states to hesitate in sharing nuclear technology with developing nations, even technology that could be used for peaceful applications. All of these concerns led to international interest in a nuclear non-proliferation treaty that would help prevent the spread of nuclear weapons.
Although the benefits to be derived from such a treaty were clear, its development was not without controversy. A ban on the distribution of nuclear technology was first proposed by Ireland in a meeting of the General Assembly of the United Nations in 1961. Although the members approved the resolution, it took until 1965 for negotiations to begin in earnest at the Geneva disarmament conference. At that time, U.S. negotiators worked to strike a delicate balance between the interest in preventing further transfer of the technology that it shared with the Soviet Union and the desire to strengthen its NATO allies by giving several Western European nations some measure of control over nuclear weapons. The plan for a nuclear NATO threatened to scuttle the talks altogether, and the United States eventually abandoned it in favor of reaching a workable treaty. A more difficult problem involved the question of bringing non-nuclear nations into line with the planned treaty. Nations that had not yet developed nuclear weapons technology were essentially being asked to give up all intentions to ever develop the weapons. Without this agreement on the part of the non-nuclear powers, having the nuclear powers vow never to transfer the technology would likely not result in any real limitation on the number of worldwide nuclear powers. After two years of negotiations, the nuclear powers managed to make enough concessions to induce many non-nuclear powers to sign.
The final treaty involved a number of provisions all aimed at limiting the spread of nuclear weapons technology. First, the nuclear signatories agreed not to transfer either nuclear weapons or nuclear weapons technology to any other state. Second, the non-nuclear states agreed that they would not receive, develop or otherwise acquire nuclear weapons. All of the signatories agreed to submit to the safeguards against proliferation established by the International Atomic Energy Agency (IAEA). Parties to the treaty also agreed to cooperate in the development of peaceful nuclear technology and to continue negotiations to help end the nuclear arms race and limit the spread of the technology. The treaty was given a 25-year time limit, with the agreement that it would be reviewed every 5 years.
The Nuclear Non-Proliferation Treaty was, and continues to be, heralded as an important step in the ongoing efforts to reduce or prevent the spread of nuclear weapons. Still, it had one major drawback in that two nuclear powers, France and the People's Republic of China, did not sign the agreement, nor did a number of non-nuclear states. Of the non-nuclear states refusing to adhere, and thereby limit their own future nuclear programs, of particular importance were Argentina, Brazil, India, Israel, Pakistan, Saudi Arabia and South Africa, because these powers were close to being capable of the technology. In fact, in 1974, India joined the "nuclear club" by exploding its first weapon. Pakistan tested its first atomic bomb in 1983.

Wednesday, February 20, 2019

Juan Enriquez has a genius level intelligence.



https://www.ted.com/talks/juan_enriquez_the_age_of_genetic_wonder_feb_2019?utm_source=newsletter_daily&utm_campaign=daily&utm_medium=email&utm_content=button__2019-02-15#t-1073878
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https://www.ted.com/talks/juan_enriquez_the_age_of_genetic_wonder_feb_2019?utm_source=newsletter_daily&utm_campaign=daily&utm_medium=email&utm_content=button__2019-02-15#t-1073878
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Des outils d'édition de gènes tels que CRISPR nous permettent de programmer la vie à son niveau le plus fondamental. Mais cela soulève des questions pressantes: si nous pouvons générer de nouvelles espèces à partir de rien, que devrions-nous construire? Devrions-nous redéfinir l'humanité telle que nous la connaissons? Juan Enriquez prévoit les futurs possibles de l'édition génétique, explorant l'immense incertitude et les opportunités de cette nouvelle frontière.
Cette conférence a été présentée à un public local à TEDxCERN , un événement indépendant. Les éditeurs de TED ont choisi de le présenter pour vous.

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